Memorial Sloan Kettering Dmg Manager
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Millions of Americans take dietary supplements for a variety of purposes, including general health, athletic performance and as alternative therapy for an illness. Dimethylglycine, a derivative of the amino acid glycine, is a less commonly known substance available as a supplement. It has antioxidant properties. People take DMG as a supplement for a number of purported benefits; however, clinical data to support most claims are lacking. Talk to your doctor before taking supplements of any kind, including DMG.
Unraveling DMG
DMG is produced as a result of metabolizing choline, an amino acid that plays a role in cell signaling, nerve transmission and fat metabolism. DMG is found naturally in certain foods like beans, cereal grains and liver. It appears that DMG plays a role in producing glutathione during fetal development, according to the Memorial Sloan-Kettering Cancer Center. Glutathione is your body's primary antioxidant.
DMG Uses
Memorial Sloan Kettering Hospital
Some people use DMG for antioxidant benefits. Antioxidants neutralize unstable atoms called free radicals, which can cause oxidative damage. This occurs when the body has more free radicals than it can handle at any given time. DMG also increases oxygenation at the cellular level, which may be why some people use it to enhance athletic performance. DMG has been used to boost the immune system, and to treat autism and chronic fatigue syndrome.
Supporting Clinical Data
Very few DMG studies exist and those that do fail to validate claims for most uses. There is no evidence that DMG improves athletic performance or chronic fatigue. Studies to support its use for autism have been mixed. DMG does provide cellular protection against formaldehyde, according to a study published in the 2009 edition of 'The Journal of Biological Chemistry.' Formaldehyde is a toxic substance naturally present in the environment, and it results from certain metabolic processes.
Points to Consider
At the very least, DMG appears to provide antioxidant benefits, but you can get antioxidants from eating a diet rich in fruits and vegetables. A recommended dose has not been established, so follow the manufacturer's instructions. DMG is non-toxic and no adverse side effects have been reported, according to the Memorial Sloan-Kettering Cancer Center. Discontinue use if you experience unwanted effects that you suspect are related to DMG.
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About the Author
Janet Renee is a clinical dietitian with a special interest in weight management, sports dietetics, medical nutrition therapy and diet trends. She earned her Master of Science in nutrition from the University of Chicago and has contributed to health and wellness magazines, including Prevention, Self, Shape and Cooking Light.